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DESCRIPTION
Chlorhexidine is active in vitro against a number of Gram positive and Gram negative bacteria, yeasts and dermatophyte fungi. At relatively low concentrations, the action of chlorhexidine is bacteriostatic. At higher concentrations the action is rapidly bactericidal. Chlorhexidine is relatively unaffected by organic debris (blood, pus, necrotic tissue etc.) Because of its cationic nature chlorhexidine has a sustained residual activity when applied to the skin.
Chlorhexidine in a detergent base (e.g. ScrubUp) is used extensively for disinfection of the hands, while alcohol-based chlorhexidine is particularly suitable for final-stage skin preparation of the peration site. The area should be kept wet for at least 2 minutes to achieve maximal effect. The immediate bactericidal action of chlorhexidine surpasses that of similar preparations containing povidone-iodine or triclosan.
Directions For Use
Chlorhexidine Concentrate 5% Solutions are normally used as follows:
This solution contains 5 grams of chlorhexidine digluconate per 100ml. It may be diluted prior to use: to obtain 1l of a 0,05% chlorhexidine solution add 10ml of Chlorhexidine 5% Concentrate
to 990ml of water. Leave solution in contact with the surface to be treated for at least 15 minutes.
COMPOSITION
Chlorhexidine digluconate 5% m/v in aqueous base.
Chlorhexidine Concentrate 5% Solution (Kyron) is bactericidal. It was effective in killing 99.9% of bacteria (P.aeruginosa,E.coli, S.aureus) within 5 minutes and 99.9% effective in killing fungi
PRESENTATION
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